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Introduction: This study aims at analyzing the effect of 12 weeks physical exercise (30 minutes for three days a week: 70-85% of the maximum heart rate) on variations of inflammation markers in middle-aged women's Coronary Heart diseases (CHDs). Methods: In this study a total of 40 subjects including 40-55 years old women were selected purposively and were divided into two experimental and control groups. The experimental group members were asked to follow a certain physical exercise program including 12 weeks physical exercise (30 minutes, three days a week with 70-85% of maximum heart rate using a treadmill); whereas subjects in the control group were asked to follow their normal lifestyle and do not change their activities and food habits. Levels of factors that can affect coronary heart risks including fibrinogen, C-reactive protein (CRP), and white blood cells (WBCs) were measured before and after exercises. Independent and paired t-tests were used to analyze data. Results: The results of this study indicated a significant decrease in fibrinogen, CRP, and WBC levels after 12 weeks physical exercise in the experimental group (P≤0.05); whereas no significant change was seen in the control group (P>0.05). Conclusion: Regarding the results of this study we can conclude that performing physical exercise (30 minutes, three days a week with 70-85% of maximum heart rate) can play an effective role in reducing risk factors of coronary heart disease (CHD) and hence in preventing coronary heart disease in 40-55 years old women with the similar properties of patients examined in this study.

واژه‌های کلیدی: Factors، Fibrinogen، C-Reactive Protein (CRP)

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