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Introduction: Denture wearingcan causea varietyoflesionsintheoral cavity, butmost of the problems can be prevented with maintaining healthyoral tissue, denture hygiene and follow up after the dentures delivery. The purpose of this study was the evaluation ofinstructional intervention effect on the incidence of oral candidiasis in complete denture wearers, and its association with age, gender and educational level in Bandar Abbas city. Methods: The present study was prospective trial-analytic. Fifty one subjects evaluated as available who willing to be treated with removable complete denture for the first time.Sampling was performed with sterile swabs from mid hard palate before inserting denture. Swabs were placed in 2ml normal saline immediately. 50μl of normal saline was inoculated on CHROM agar candida medium. After 48-72 hrs colonies were counted and subjects divided to healthy, carrier, afflicted. In the absence of candidiasis subjects were divided in to three groups. One groups received verbal instruction, second group received pamphlet and the last group received CD. Second and third tests were repeated in the first week and fourth month after they worn dentures. Results: The minimum rate of candidiasis was zero percentage among those who had been instructed verbally. The highest incidence (16.7%) was in those who were instructed by pamphlet. There was no difference between three groups in incidence of oral candidiasis (P=0.21). There was the same effect to negative the carriers before and after first intervention in three groups (P=0.55). Verbal instruction had significant effect in to negative the carriers in second intervention compared to the first time (P=0.45). There were no difference between types of instruction and age and gender (P=0.62, P=0.62). All of subjects were diagnosed candidiasis had under Diploma education (10.3). The relationship between the education level of subjects and incidence of oral candidiasis were significant statistically (P=0.43). Conclusion: Hygiene instruction should be instructed in accordance the culture of the regions. Efforts to improve the education can promote health.

Keywords: Oral Candidiasis, Denture, Pamphlets

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