Hormozgan Medical Journal
مجله پزشکی هرمزگان
Hormozgan Medical Journal
Medical Sciences
http://hmj.hums.ac.ir
1
admin
2423-3528
2423-3536
doi
en
jalali
1394
1
1
gregorian
2015
4
1
19
1
online
1
fulltext
en
Protective effects of purslane seed (Portulaca Oleracea L.) on plasma levels of Cystatin C, Cathepsin S, and Creatinine in women with type 2 Diabetes
Protective effects of purslane seed (Portulaca Oleracea L.) on plasma levels of Cystatin C, Cathepsin S, and Creatinine in women with type 2 Diabetes
عمومى
General
پژوهشي
Research
Introduction: Diabetes is a chronic metabolic disease which is associated with the inflammation of cardiovascular system and kidney. Studies have shown that medicinal plants could be effective in reducing inflammation; however, the effectiveness of purslane (Portulaca oleracea) on inflammation is not well defined. Thus, this study attempted to investigate the effect of Portulaca oleracea seed consumption on plasma levels of cystatin C, cathepsin S, and creatinine in women with type 2 diabetes. Methods: In this quasi-experimental study, 14 women with type 2 diabetes were randomly divided into two equal groups of intervention and control (n=7). The subjects received Portulaca oleracea seed 2.5 g at lunch and 5 g at dinner (totally 7.5 g) per day for 8 weeks. Blood was collected before and 48 hours after the last intervention. Data were analyzed with paired and independent t-tests, and P<0.05 was considered significant. Results: Levels of cystatin C, cathepsin S, creatinine, and lipid profile decreased significantly in the intervention group after 8 weeks (P<0.05). There was also a significant difference between the intervention and control groups in levels of cystatin C and cathepsin S. Conclusion: Changes in biochemical markers showed that Portulaca oleracea seed could improve the levels of cardiovascular and kidney damage biomarkers and lipid profile in diabetic patients. However, further research is needed for more accurate conclusions.
Introduction: Diabetes is a chronic metabolic disease which is associated with the inflammation of cardiovascular system and kidney. Studies have shown that medicinal plants could be effective in reducing inflammation; however, the effectiveness of purslane (Portulaca oleracea) on inflammation is not well defined. Thus, this study attempted to investigate the effect of Portulaca oleracea seed consumption on plasma levels of cystatin C, cathepsin S, and creatinine in women with type 2 diabetes. Methods: In this quasi-experimental study, 14 women with type 2 diabetes were randomly divided into two equal groups of intervention and control (n=7). The subjects received Portulaca oleracea seed 2.5 g at lunch and 5 g at dinner (totally 7.5 g) per day for 8 weeks. Blood was collected before and 48 hours after the last intervention. Data were analyzed with paired and independent t-tests, and P<0.05 was considered significant. Results: Levels of cystatin C, cathepsin S, creatinine, and lipid profile decreased significantly in the intervention group after 8 weeks (P<0.05). There was also a significant difference between the intervention and control groups in levels of cystatin C and cathepsin S. Conclusion: Changes in biochemical markers showed that Portulaca oleracea seed could improve the levels of cardiovascular and kidney damage biomarkers and lipid profile in diabetic patients. However, further research is needed for more accurate conclusions.
Cystatin C,Cathepsin S,Creatinine,Diabetes,
Cystatin C,Cathepsin S,Creatinine,Diabetes,
1
8
http://hmj.hums.ac.ir/browse.php?a_code=A-10-2-1558&slc_lang=en&sid=1
Parvin
Farzanegi
Parvin
Farzanegi
No
Maryam Shaerani
Shaerani
Maryam Shaerani
Shaerani
No
Mohammad Ali
Azarbayjani
Mohammad Ali
Azarbayjani
No