Hormozgan Medical Journal
مجله پزشکی هرمزگان
Hormozgan Medical Journal
Medical Sciences
http://hmj.hums.ac.ir
1
admin
2423-3528
2423-3536
doi
en
jalali
1395
9
1
gregorian
2016
12
1
20
5
online
1
fulltext
en
Influence of glutamine supplementation on muscle damage and oxidative stress indices following 14km running
Influence of glutamine supplementation on muscle damage and oxidative stress indices following 14km running
عمومى
General
پژوهشي
Research
Introduction: The aim of this study was to evaluate effects of 7 day glutamine supplementation on exercise-induced oxidative stress and muscle damage. Methods: Nineteen healthy, nonsmoking, young men were recruited to participate in this study. Participants were randomized in a double-blind placebo-controlled fashion into 2 groups: Glutamine (G group) (n=9) and placebo (P group) (n=10). Subjects consumed daily either glutamine (1.5 g/kg glutamine+250ml water+15g sweetener) or placebo (250ml water+15g sweetener) for 7days. Then, participants ran 14km and were allowed to consume water throughout the exercise. Blood samples were taken before supplementation, before exercise, immediately, and 1h after exercise. Results: Creatine kinase (CK) significantly increased in both groups after exercise compared with pre-exercise (P<0.05). Moreover, there was a significant CK increase in P group compared with the G group 1h after exercise (P=0.021). TAC significantly increased immediately post-exercise compared with pre-exercise just in the G group (P<0.05). There was significant reduced glutathione (GSH) increase in the G group after supplementation, immediately, and 1h after exercise, but just 1h after exercise in P group compared with baseline (P<0.05). Malondealdehyde (MDA) significantly increased 1h after exercise compared with pre-exercise just in P group (P<0.05). There was any within or between groups’ differences in serum total bilirubin (P>0.05). Conclusion: It seems 7 day glutamine supplementation has been able to affect oxidative stress and muscle damage markers via possibly an effect on antioxidant agents.
Introduction: The aim of this study was to evaluate effects of 7 day glutamine supplementation on exercise-induced oxidative stress and muscle damage. Methods: Nineteen healthy, nonsmoking, young men were recruited to participate in this study. Participants were randomized in a double-blind placebo-controlled fashion into 2 groups: Glutamine (G group) (n=9) and placebo (P group) (n=10). Subjects consumed daily either glutamine (1.5 g/kg glutamine+250ml water+15g sweetener) or placebo (250ml water+15g sweetener) for 7days. Then, participants ran 14km and were allowed to consume water throughout the exercise. Blood samples were taken before supplementation, before exercise, immediately, and 1h after exercise. Results: Creatine kinase (CK) significantly increased in both groups after exercise compared with pre-exercise (P<0.05). Moreover, there was a significant CK increase in P group compared with the G group 1h after exercise (P=0.021). TAC significantly increased immediately post-exercise compared with pre-exercise just in the G group (P<0.05). There was significant reduced glutathione (GSH) increase in the G group after supplementation, immediately, and 1h after exercise, but just 1h after exercise in P group compared with baseline (P<0.05). Malondealdehyde (MDA) significantly increased 1h after exercise compared with pre-exercise just in P group (P<0.05). There was any within or between groups’ differences in serum total bilirubin (P>0.05). Conclusion: It seems 7 day glutamine supplementation has been able to affect oxidative stress and muscle damage markers via possibly an effect on antioxidant agents.
Glutamine,Muscle Damage,Creatine Kinase (CK),
Glutamine,Muscle Damage,Creatine Kinase (CK),
0
0
http://hmj.hums.ac.ir/browse.php?a_code=A-10-2-1520&slc_lang=en&sid=1
Babak
Nakhostin-Roohi
Babak
Nakhostin-Roohi
No
Rasool
Javanamani
Rasool
Javanamani
No
Navid
Zardoost
Navid
Zardoost
No
Raziyeh
Ramazanzadeh
Raziyeh
Ramazanzadeh
No