Volume 16, Issue 1 (Apr and Sep 2012)                   hmj 2012, 16(1): 17-24 | Back to browse issues page

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Alahtavakoli M, Vazirinejad R, Ansari Jaberi A, Negahban T, Mashayekhi H, Nazari M, et al . Effect of Teucrium polium extract on skin wound healing in rat. hmj. 2012; 16 (1) :17-24
URL: http://hmj.hums.ac.ir/article-1-53-en.html
Associate Professor Department of Physiology , Physiology & Pharmacology Research Center
Abstract:   (7444 Views)
Introduction: Teucrium polium (TP) is a plant which its anti-inflammatory and antimicrobial properties has been widely reported. In the present experiment, effect of hydroalcoholic extract of TP on skin wound healing in rats is investigated.
Methods: 30 wistar rats randomly divided in 3 equal groups as follow: control (saline), 50 and 100 mg/ml of TP extract. One day after wounds induction, they were locally applied with saline (control), TP 50 mg/ml, or TP 100 mg/ml, accordingly. Wound areas were measured on days 1, 5, 9, 13 and 17. Data were analyzed using ANOVA for repeated measured data.
Results: Wound area between control and both doses of TP extract was significantly different at 9th (P<0.005), 13th (P<0.005) and 17th (P<0.001) days. Wound healing percent between control and both doses of TP was also significantly different at 5th, 9th, 13th days (P<0.001), and 17th day (P<0.005). Furthermore, a significant different was shown between control and TP doses in the duration of complete wound healing (P<0.001).
Conclusion: hydro-alcoholic extract of Teucrium polium accelerates skin wound healing process and decreases the duration of complete wound healing.
Keywords: Teucrium Plium, Wounds, Rat
Full-Text [PDF 248 kb]   (1669 Downloads)    
Type of Study: Research | Subject: General
Received: 2012/10/17

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