Volume 8, Number 4 (Winter 2005)                   hmj 2005, 8(4): 193-197 | Back to browse issues page


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Emamghoreishi F. The prognosis of lupus nephritis in children. hmj. 2005; 8 (4) :193-197
URL: http://hmj.hums.ac.ir/article-1-310-en.html

Abstract:   (9893 Views)
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors.
Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were calculated.
Results: The patients were aged 3-11 years. All of the patients had proteinuria and hematuria at the time of presentation. The most common type of renal pathology was class IV lupus nephritis. In follow up, 29.2% and 25% of patients had chronic renal failure and hypertension respectively. The most significantly associated factor was the presence of hypertension at the time of presentation (p=0.03). Five year renal survival rate was 63.8%.
Conclusion: Age, sex and renal pathology prevalence of children with lupus nephritis in present study is similar to other studies. Hypertension is a significant predictive factor, so it needs more attention for early treatment of hypertensive patient with lupus nephritis. Less favorite renal outcomes in the present study needs more investigation
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Type of Study: Research | Subject: General
Received: 2012/10/24

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