Volume 11, Number 3 (Autumn 2007)                   hmj 2007, 11(3): 207-212 | Back to browse issues page


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Owlia M, Sami R, Salimzadeh A. Cryoglobulinemia in patients with hepatitis C. hmj. 2007; 11 (3) :207-212
URL: http://hmj.hums.ac.ir/article-1-213-en.html

Abstract:   (8332 Views)
Introduction: Cryoglobulinemia is a kind of immunoglobuline that form in various conditions. These imunoglobulines, precipitate in cold environment and restore to soluble state upon rewarming. Nowadays, strong association between cryoglobulines and hepatitis C has been proposed.
Methods: This is a descriptive-analytic study in which we included all documented cases of hepatitis C infection who referred to Shahid Sadoughi Hospital from May 2004 to December 2005. Their sera was assessed for cryoglobulines. Results were analyzed by SPSS software and using Chi-square and t-test.
Results: Fifty patients entered the study while 8 persons (15%) were positive for cryoglobulines. No statistically significant correlation was shown between positive cryoglobulinemia and age, sex, mode of acquiring infection, liver enzyme titer, HBs antigen and anti-HIV antibody.
Conclusion: Regarding the clinical significance of cryoglobolinemia in developing different clinical syndromes, it is recommended to evaluate cryoglobulines in high risk groups, especially patients with hepatitis C
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Type of Study: Research | Subject: General
Received: 2012/10/21

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