Volume 21, Issue 4 (Oct-Dec 2017)                   hmj 2017, 21(4): 278-287 | Back to browse issues page


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Eizadi M, Behboudi L. Modulatory effect of aerobic training on some inflammatory profile indicators in obese females. hmj. 2017; 21 (4) :278-287
URL: http://hmj.hums.ac.ir/article-1-1803-en.html
Department of Exercise Physiology, Saveh Branch, Islamic Azad University, Saveh, Iran.
Abstract:   (517 Views)
Introduction: It is widely accepted that low grade systemic inflammation plays a key role in obesity and related diseases and metabolic syndrome. The objective of this work was to evaluate the effect of aerobic training intervention on CRP and IL-10 in adult obese females.
Methods: Thirty adult obese women (30≤BMI≤36) aged 30 to 40 years were randomly assigned to exercise (3 months aerobic training, 3 time per week at 60-75% of maximum heart rate, n=15) and control (no training, n=15). At baseline and after 3 months, anthropometrical indexes as well fasting serum IL-10 and CRP were assessed in 2 groups. Inter and intra-group changes were analyzed by independent and paired sample T test. P<0.05 was considered statistically signigcant.
Results: After the 3 months of aerobic intervention, a significant decrease were observed in BMI, abdominal circumference, body weight, body fat (%) and visceral fat of exercise subjects (P<0.05). No significant difference was found in all variables between 2 groups at baseline (P>0.05). Aerobic intervention resulted in significant increase in serum IL-10 (from 14.79±3.04 to 17.79±3 pg/ml, P=0.001) and decrease in CRP (from 5670±1971 to 3848±1092 ng/ml, P=0.002). All variables remained no change in control subjects (P>0.05).
Conclusion: With emphasis on IL-10 and CRP, long-term aerobic training can be considered as a anti-inflammatory treatment in sedentary obese females.
Keywords: Aerobic Exercise, Adipose Tissue, Inflammation, Weight Loss
Eizadi M, Behboudi L. Modulatory effect of aerobic training on some inflammatory profile indicators in obese females. Hormozgan Medical Journal 2017;21(4):278-287.
Full-Text [PDF 584 kb]   (216 Downloads)    
Type of Study: Research | Subject: medical
Received: 2018/03/13 | Accepted: 2018/03/13 | Published: 2018/03/13

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