Volume 24, Issue 2 (6-2020)                   2020, 24(2): 0-0 | Back to browse issues page

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Gholami F, Bashiri J, Amanollahi N. Anti-Inflammatory Effects of Garlic Consumption and Regular Exercise in Sedentary Overweight Individuals. Hormozgan Medical Journal 2020; 24 (2)
URL: http://hmj.hums.ac.ir/article-1-1173-en.html
Abstract:   (41 Views)
Background: A sedentary lifestyle can result in chronic inflammation, which is a risk factor for Cardiovascular Disease (CVD). Lifestyle modifications, including physical activity and herbal supplements, may have health benefits. Objectives: The present study aimed to investigate the effect of regular exercise and garlic consumption on some inflammatory biomarkers in sedentary overweight individuals. Methods: Forty-four sedentary overweight male participants (20 - 30 years) were randomized to the following groups: Exercise + garlic (ES), exercise + placebo (E), garlic (G), and placebo (P). The training protocol included 20 - 45 minutes of walking/running at 60 to 75% of the maximum heart rate, three sessions per week for eight weeks. Participants consumed two capsules containing 500 milligrams of garlic powder or placebo (starch) per day. Before and 48 h after the exercise intervention and supplement administration, blood samples were collected to assess the hs-CRP and TNF-α serum levels. One-way ANOVA and Tukey’s post hoc tests were used to analyze the data at a significance level of P < 0.05. Results: A significant difference was observed between the groups regarding the hs-CRP and TNF-α levels after the experimental period (P < 0.05). There was a significant difference between EG and placebo groups (P < 0.05). Conclusions: Based on the findings, garlic consumption, along with exercise training could exert anti-inflammatory properties in overweight subjects.
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Type of Study: Research | Subject: General
Received: 2024/02/11

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